Spondylitis is one of the leading causes of back and neck pain and is most commonly the result of an inflammation of the vertebral joints. It develops very silently and comes to prominence when the condition has fully developed. Pain in spondylitis is generally concentrated around the cervical region of the neck, shoulder and lower spine with the stings and instances of pain flowing further downwards.
Enthesitis (inflammation of the place where muscles and ligaments connect to bones) accounts for much of the pain and stiffness of ankylosing spondylitis (AS). This inflammation eventually leads to bony fusion of the joints.
Other joints can also develop the inflammation of the lining of the joint (synovitis), with lower limb joints commonly involved than upper-limb joints. Ankylosing spondylitis often develops in young adult men and it may last a lifetime.
Pain in the lower back and buttocks are the prime symptoms of ankylosing spondylitis (AS). In contrast to mechanical low back pain, stiffness and low back pain in AS patients are worse after a period of rest or on waking up in the morning. It improves after exercise and a hot bath or a shower. Progressive stiffening of the spine is common, with ankylosis (fusion of some or all spinal joints) emerging after some years of disorder in many, but not all, patients. The most of patients have mild or moderate disorder with intermittent exacerbations and suspension and maintain some mobility and independence throughout life.